Time to Euromit 2023

Young Investigators Meeting

Bologna Volvo Congress – June 10, 2023

Introduction

The Young Investigators Meeting is going to be an amazing occasion for young investigators to meet personalities in the field of mitochondrial pathology.

The meeting is a joint collaboration between Euromit 2023 and Mitocon, the Italian Patients’ Association.

One of the sessions will be dedicated to oral presentations of young investigators (35 years old or less) chosen between those who submitted an abstract for Euromit 2023. The choice will be communicated at the beginning of May (the exact date will be announced soon). The other abstracts will be discussed during a round table that will bring together all young investigators, present professionals, and editors in an engaging discussion.

The idea of the Young Investigator Meeting comes from a group of young researchers and clinicians. Their desire to be involved, share knowledge and collaborate to create an international network, led to the foundation of a Committee of 10 members, from the Czech Republic, France, Italy, and Spain.

The goal is to repeat the experience of the Young Investigator Meeting around the world and to contribute to the growth of the next generation of researchers and clinicians.

Price: the Meeting is included in all registration fees.

Scientific Programme Committee

Aleksandra Markovic, Department of Bioenergetics, Institute of Physiology, Czech Academy of Science, Prague, Czech Republic

Alessia Di Donfrancesco, IRCCS Istituto Neurologico Carlo Besta, Milan, Italy

Andrea Cavaliere, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy

Claudio Fiorini, IRCCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy

Giada Capirossi, Department of Biomedical And Neuromotor Sciences, University of Bologna; IRRCS Istituto delle Scienze Neurologiche di Bologna, Bologna, Italy

Maria Illescas, Department of Rare, Neuromuscular and Mitochondrial Disorders, Fundación Investigación 12 de Octubre, Madrid

Melanie Abou-Ali, Institute for Research on Cancer and Aging (IRCAN), Nice, France

Piervito Lopriore, Department of Clinical and Experimental Medicine, Neurological Clinic, University of Pisa, Pisa, Italy

Sandra Lopez, Department of Rare, Neuromuscular and Mitochondrial Disorders, Fundación Investigación 12 de Octubre, Madrid

Willian Meira, Institute for Research on Cancer and Aging (IRCAN), Nice, France

Programme

09.00 – 10.00 – Registration

10:00 – 10:15 – Welcome from the Committee

  • Euromit Chairs: Valeria Tiranti, Valerio Carelli
  • Founder Mitocon: Piero Santantonio

10:15 – 11:15 – Session 1: Basic Science
Moderators: Cristina Ugalde, Melanie Abou-Ali

10:15 – 10:35 – Luisa Iommarini: Two ways, same target: what can we learn from TMEM126A?

10:35 – 10:45 – Samuel Louis Del’Olio: Mitoribosome intrinsic GTPase mS29 acts as a non-canonical molecular switch to facilitate mitochondrial translation

10:45 – 10:55 – Kevin McAvoy: Investigating the function of CHCHD2-CHCHD10 complexes in mitochondria

10:55 – 11:15 – Discussion

11:15-12:15 – Session 2: Translational Research
Moderators: Valeria Tiranti, Andrea Cavaliere

11:15 – 11:35 – Alessandro Prigione: How to capture mitochondrial phenotypes in stem cells and organoids model

11:35 – 11:45 – Claudio Fiorini: Recessive MECR pathogenic variants cause a LHON-like optic neuropathy

11:45 – 11:55 – Pesini Alba: Cultured neurons with CoQ10 deficiency reveal alterations of lipid metabolism

11:55 – 12:15 – Discussion

12:15 – 13:15 – Session 3: Progress in Therapies
Moderators: Valerio Carelli, Alessia Di Donfrancesco

12:15- 12:35 – Michal Minczuk: Current progress in the therapeutics option for mitochondrial disorders

12:35 – 12:45 – Pilar Gonzalez-Garcia: Therapeutic interventions to regulate the Q-junction, 1C metabolism and the neuroinflammatory response

12:45 – 12:55 – Walker Brittni Rae: CNS gene therapy in a mouse model of complex I encephalopathy

12:55-13:15 – Discussion

13:15 – 14:30 – Lunch

14:30 – 16:30 – Session 4: Round Table Poster Session with editor
Moderators: Alessia Di Donfrancesco, Claudio Fiorini

Active discussion of posters with the participation of journals Editors, available for Q&A:

  • Shamima Rahman (JIMD)
  • Rita Horvath (Brain)
  • Zeljko Durdevic (EMBO Mol Med)

Coffee Break (during the poster session)

16:30 – 18:00 – Mentoring Session by invited speakers

Invited speakers will host a non-scientific session with a discussion about career planning, publishing, etc.

16:30 – 17:00 Luca Scorrano

17:00 – 17:30 Shamima Rahman

17:30 – 18:00 Cristina Ugalde

18:00 End of the day